Expression Pattern of DMRT1 and STRA8 Genes During Postnatal Development of Rabbit Testes

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1 Department of Anatomy and Embryology, Faculty of Veterinary Medicine, Benha Univer- sity, Moshtohor 13736, Egypt.

2 Department of Anatomy and Embryology, Faculty of Veterinary Medicine, Benha University, Moshtohor 13736, Egypt.

Abstract

Abstract
Thirty New Zealand rabbits of vari- ous ages were used for this investi- gation. DMRT1 and STRA8 genes expression was recorded by RT PCR, completed by histological sec- tions of testes in studied ages. DMRT1 and STRA8 genes have dis- tinct roles during spermatogenesis in mammals. The present study hy- pothesized that the change in the level of specific genes expression during spermatogenesis could be re- lated to the change in the comple- ment of germ cell types. Distinct ex- pression patterns were observed for DMRT1 reached the maximum level (peak or plateau) just before sper- matogenesis process at age of 6.5thweek and testicular STRA8 reachedthe maximum level at 6 months. The two genes expression patterns are consistent with their specific roles during spermatogenesis. The pur- pose of the present study was to de- termine the expression of DMRT1


and STRA8 genes throughout post- natal New Zealand rabbit testis thatwould serve as a reference for ex- pression pattern of the studied genes.

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